PD 123,319 di(trifluoroacetate) salt hydrate, powder, >=98% (HPLC)

Code: p186-10mg D2-231

Not available outside of the UK & Ireland.

Application

PD123,319 di (trifluoroacetate) salt hydrate has been used in following experimental studies:To determine the effect of Angiotensin II (Ang II) on alveolar fluid ...


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Your Price
£287.00 10MG
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Not available outside of the UK & Ireland.

Application

PD123,319 di (trifluoroacetate) salt hydrate has been used in following experimental studies:To determine the effect of Angiotensin II (Ang II) on alveolar fluid clearance (AFC).To study the effect of PD123319 on AngII-induced abdominal aortic aneurysms (AAAs).To study its effect on Ang II-induced LRP1 overexpression and function in vascular smooth muscle cells (VSMCs) culture.

Biochem/physiol Actions

PD123,319 di (trifluoroacetate) salt hydrate is a widely used angiotensin II subtype-2 receptor (AT2R) antagonist to study the role of AT2 receptor in vitro and in vivo. It increases the AngII-induced abdominal aortic aneurysms (AAAs) without interacting with AT2 receptor.

Caution

Hygroscopic

Legal Information

Sold with permission of Warner-Lambert Company.

Packaging

10 mg in poly bottle

assay≥98% (HPLC)
formpowder
InChI keyPTSUEYBWHKDYBS-FPCIESGBSA-N
InChI1S/C31H32N4O3.2C2HF3O2.H2O/c1-21-16-22(14-15-26(21)33(2)3)18-34-20-32-25-19-35(28(31(37)38)17-27(25)34)30(36)29(23-10-6-4-7-11-23)24-12-8-5-9-13-24;2*3-2(4,5)1(6)7;/h4-16,20,28-29H,17-19H2,1-3H3,(H,37,38);2*(H,6,7);1H2/t28-;;;/m0.../s1
SMILES stringO.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c4ccccc4)c5ccccc5)cc1C
solubilityH2O: 10 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
Cas Number130663-39-7
This product has met the following criteria: