[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder

Code: l4513-1mg D2-231

Not available outside of the UK & Ireland.

Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Ala-Leu-Arg-Pro-NHEt

Application

[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate has been used:...


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£82.40 1MG
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Not available outside of the UK & Ireland.

Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Ala-Leu-Arg-Pro-NHEt

Application

[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate has been used: as an luteinizing hormone-releasing hormone (LHRH) agonist to synchronize a cohort of females ratsto synchronize naturally cycling rats to induce ovulation as a gonadotropin-releasing hormone (GnRH) analogue and as a supplement in Galap extender to dilute qualified ejaculate

Biochem/physiol Actions

Potent LH-RH agonist in rats and mice; reversibly delays sexual maturation in rats, stimulates spawning activity in fish. GnRH ( gonadotropin-releasing hormone, Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

assay≥97% (HPLC)
formpowder
Gene Informationmouse ... GNRH1(2796), GNRHR(2798)rat ... GNRH1(14714), GNRHR(14715)
InChI keyYEEHIOYEWOESQR-PFHUABGLSA-N
InChI1S/C56H78N16O12.C2H4O2.H2O/c1-5-60-54(83)45-13-9-21-72(45)55(84)39(12-8-20-61-56(57)58)66-50(79)40(22-30(2)3)67-47(76)31(4)64-49(78)41(23-32-14-16-35(74)17-15-32)68-53(82)44(28-73)71-51(80)42(24-33-26-62-37-11-7-6-10-36(33)37)69-52(81)43(25-34-27-59-29-63-34)70-48(77)38-18-19-46(75)65-38;1-2(3)4;/h6-7,10-11,14-17,26-27,29-31,38-45,62,73-74H,5,8-9,12-13,18-25,28H2,1-4H3,(H,59,63)(H,60,83)(H,64,78)(H,65,75)(H,66,79)(H,67,76)(H,68,82)(H,69,81)(H,70,77)(H,71,80)(H4,57,58,61);1H3,(H,3,4);1H2/t31-,38+,39+,40+,41+,42+,43+,44+,45+;;/m1../s1
Quality Level100
SMILES stringO.CC(O)=O.CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc5c[nH]cn5)NC(=O)[C@@H]6CCC(=O)N6
storage temp.−20°C
UniProt accession no.P01148, P30968, Q01776, P13562
Code
Description
Unit Size
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L4513-25MG
[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder

Unit:25MG
List Price: £1,040.00
Source:List Price
ADD
L4513-5MG
[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate, >=97% (HPLC), powder

Unit:5MG
List Price: £305.00
Source:List Price
ADD
Cas Number52435-06-0
This product has met the following criteria: