Not available outside of the UK & Ireland.

Biochem/physiol Actions

Protein kinase C ι (PKCι) is involved in Ras signaling. In colonic epithelium, it is an important regulator of oncogenic Ras. Transgenic mice which are constitutively expressing PKCι are at high risk of carcinogen-mediated colon carcinogenesis.

General description

PKCι (protein kinase C ι) belongs to the protein kinase C family.

Legal Information

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Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.