Resorufin ethyl ether,

Code: e3763-1mg D2-231

Not available outside of the UK & Ireland.

Application

Resorufin ethyl ether is suitable for the study of dealkylating activity of cytochrome P450 isozymes 1A1 and 1A2, where arylalkyl and alkyl isothiocyanates, and t...


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$110.40 1MG
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Not available outside of the UK & Ireland.

Application

Resorufin ethyl ether is suitable for the study of dealkylating activity of cytochrome P450 isozymes 1A1 and 1A2, where arylalkyl and alkyl isothiocyanates, and their glutathione, cysteine, and A′-acetylcysteine conjugates are used as inhibitors. It is suitable to study the ethoxyresorufin-O-deethylase (EROD) activity of cytochrome P450 activity (CYP1A1).

General description

Resorufin ethers are used as markers or substrates for different cytochrome P (CYP) isoforms. Resorufin ethyl ether is the preferred resorufin ether to be metabolized by microsomes of 3-methylcholanthrene treated animals.

Resorufin is the reduced product of resazurin, also termed as Alamar Blu. It exhibits fluorescence at longer wavelengths and is flexible for modification in its hydroxyl group.

Packaging

1, 5 mg in glass bottle

Substrates

Fluorimetric substrate for cytochrome P450 linked enzyme, CXPIA1/2

assay≥98% (TLC)
formpowder
InChI keyZOSYTBPPLWBBKM-UHFFFAOYSA-N
InChI1S/C23H14F5NO4.C14H11NO3/c24-17-18(25)20(27)22(21(28)19(17)26)33-16(30)9-29-23(31)32-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15;1-2-17-10-4-6-12-14(8-10)18-13-7-9(16)3-5-11(13)15-12/h1-8,15H,9-10H2,(H,29,31);3-8H,2H2,1H3
mp223-225 °C (lit.)
Quality Level200
SMILES stringCCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1.Fc4c(F)c(F)c(OC(=O)CNC(=O)OCC5c6ccccc6-c7ccccc57)c(F)c4F
solubilitychloroform: 9.80-10.20 mg/mL, clear, orange
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
E3763-5MG
Resorufin ethyl ether,

Unit:5MG
List Price: $382.21
Source:List Price
ADD
Cas Number5725-91-7
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