Cecropin p1 porcine

Code: c7927-.1mg D2-231

Not available outside of the UK & Ireland.

Amino Acid Sequence

Ser-Trp-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-Ala-Lys-Lys-Arg-Ile-Ser-Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg

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Not available outside of the UK & Ireland.

Amino Acid Sequence

Ser-Trp-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-Ala-Lys-Lys-Arg-Ile-Ser-Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg

Application

Cecropin P1 Porcine has been used to study its antimicrobial activity against Escherichia coli.

Biochem/physiol Actions

Cecropin P1 can inhibit the growth of enterotoxigenic Escherichia coli in porcine. It also can inhibit the growth of human fungal pathogen Candida albicans. Cecropin P1 also blocks the release of viral particles and impairs virus-induced apoptosis. Cecropins are cationic anti-microbial peptides (AMPs). It can inactivate microorganisms by forming an α-helical chain which punctures the cell membrane. Cecropins may be used in food preservation as it is non-cytotoxic to mammalian cells.

Antibacterial peptide originally identified in moths (Hyalophora cecropia) and later in pig intestine.

General description

Cecropin P1 is found in Ascaris suum, which is a parasite that lives in porcine intestine.

antibiotic activity spectrumfungi
assay≥95% (HPLC)
formpowder
InChI keyPRIVBYDFWSFUFP-UHFFFAOYSA-N
InChI1S/C147H253N45O43/c1-18-75(9)113(140(229)167-81(15)120(209)188-114(76(10)19-2)141(230)168-82(16)121(210)189-115(77(11)20-3)142(231)178-94(47-50-106(154)198)123(212)164-66-108(200)163-68-110(202)192-60-36-46-105(192)139(228)179-97(145(234)235)45-35-59-161-147(158)159)187-109(201)67-165-124(213)95(48-51-111(203)204)176-138(227)104(72-196)186-143(232)116(78(12)21-4)190-130(219)93(44-34-58-160-146(156)157)174-127(216)90(41-26-31-55-150)172-125(214)88(39-24-29-53-148)170-118(207)79(13)166-136(225)102(70-194)184-135(224)101(64-107(155)199)183-129(218)96(49-52-112(205)206)177-132(221)98(61-73(5)6)181-128(217)91(42-27-32-56-151)173-126(215)89(40-25-30-54-149)171-119(208)80(14)169-144(233)117(83(17)197)191-131(220)92(43-28-33-57-152)175-137(226)103(71-195)185-133(222)99(62-74(7)8)182-134(223)100(180-122(211)86(153)69-193)63-84-65-162-87-38-23-22-37-85(84)87/h22-23,37-38,65,73-83,86,88-105,113-117,162,193-197H,18-21,24-36,39-64,66-72,148-153H2,1-17H3,(H2,154,198)(H2,155,199)(H,163,200)(H,164,212)(H,165,213)(H,166,225)(H,167,229)(H,168,230)(H,169,233)(H,170,207)(H,171,208)(H,172,214)(H,173,215)(H,174,216)(H,175,226)(H,176,227)(H,177,221)(H,178,231)(H,179,228)(H,180,211)(H,181,217)(H,182,223)(H,183,218)(H,184,224)(H,185,222)(H,186,232)(H,187,201)(H,188,209)(H,189,210)(H,190,219)(H,191,220)(H,203,204)(H,205,206)(H,234,235)(H4,156,157,160)(H4,158,159,161)
mode of actioncell membrane | interferes
Quality Level200
SMILES stringCCC(C)C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(N)CO)C(C)O)C(C)CC)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CCCNC(N)=N)C(O)=O
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
C7927-.5MG
Cecropin P1 Porcine, >=95% (HPLC), powder

Unit:EACH
List Price: £566.00
Source:List Price
ADD
Cas Number125667-96-1
This product has met the following criteria: