Z-Leu-Leu-Norvalinal, >=90% (HPLC), powder

Code: c6706-1mg D2-231

Not available outside of the UK & Ireland.

Amino Acid Sequence

Z-Leu-Leu-Nva

Biochem/physiol Actions

Potent inhibitor of the 20S proteasome (Ki = 21 nM) and 26S proteasome (K

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Your Price
£109.00 1MG
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Not available outside of the UK & Ireland.

Amino Acid Sequence

Z-Leu-Leu-Nva

Biochem/physiol Actions

Potent inhibitor of the 20S proteasome (Ki = 21 nM) and 26S proteasome (Ki = 35 nM). Cells treated with 54 µM N-CBZ-Leu-Leu-Norvalinal showed complete block of the G1/S and metaphase transitions and delayed passage through S-phase. Induces apoptosis in Rat-1 and PC12 cells, perhaps by accumulation of stabilized p53.

Packaging

1, 5 mg in serum bottle

assay≥90% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... PSMA1(5682), PSMC1(5700)mouse ... PSMA1(26440), PSMC1(19179)rat ... PSMA1(29668), PSMC1(117263)
InChI keyQEJRGURBLQWEOU-FKBYEOEOSA-N
InChI1S/C25H39N3O5/c1-6-10-20(15-29)26-23(30)21(13-17(2)3)27-24(31)22(14-18(4)5)28-25(32)33-16-19-11-8-7-9-12-19/h7-9,11-12,15,17-18,20-22H,6,10,13-14,16H2,1-5H3,(H,26,30)(H,27,31)(H,28,32)/t20-,21-,22-/m0/s1
Quality Level100
SMILES stringCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O
solubilityDMSO: soluble
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
C6706-5MG
Z-Leu-Leu-Norvalinal, >=90% (HPLC), powder

Unit:5MG
List Price: £248.00
Source:List Price
ADD
Cas Number133407-86-0
This product has met the following criteria: