N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, >=95% (HPLC), powder

Code: a5845-5mg D2-231

Not available outside of the UK & Ireland.

Amino Acid Sequence

NAc-Leu-Glu-His-Asp-AFC

Application

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin has been used to assa...


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$290.84 5MG
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Not available outside of the UK & Ireland.

Amino Acid Sequence

NAc-Leu-Glu-His-Asp-AFC

Application

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin has been used to assay caspase 9 activity using a substrate-based fluorimetric detection assay

General description

Amino acid derivatives of 7-amido-4-trifluoromethylcoumarin (AFC) are blue in fluorescence microscopy.

assay≥95% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... CARD9(64170), CASP9(842)mouse ... CARD9(332579), CASP9(12371)rat ... CARD9(64171), CASP9(58918)
InChI keyHULKIXRFKRCRHD-ZJZGAYNASA-N
InChI1S/C33H38F3N7O11/c1-15(2)8-22(39-16(3)44)31(52)41-21(6-7-26(45)46)29(50)42-23(9-18-13-37-14-38-18)32(53)43-24(12-27(47)48)30(51)40-17-4-5-19-20(33(34,35)36)11-28(49)54-25(19)10-17/h4-5,10-11,13-15,21-24H,6-9,12H2,1-3H3,(H,37,38)(H,39,44)(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,45,46)(H,47,48)/t21-,22-,23-,24-/m0/s1
Quality Level200
SMILES stringCC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3c(OC(=O)C=C3C(F)(F)F)c2
solubilityDMSO/DMF: 20 mM
storage temp.−20°C
This product has met the following criteria: