Not available outside of the UK & Ireland.

Analysis Note

The biological activity is measured by its ability to inhibit serum deprivation induced apoptosis in HUVE cells.

Biochem/physiol Actions

Ang-1 is a ligand with affinity to the Tie-2 receptor tyrosine kinase, which is expressed in early hematopoietic and endothelial cells. Both Ang-1 and Tie-2 play critical roles in embryonic angiogenesis as well as adult vascular integrity.

Packaging

25 µg in glass insert

Physical form

Lyophilized from a 0.2 µm filtered solution in 50 mM Tris and 0.5 M sodium chloride, pH 6.5, containing 50 µg bovine serum albumin per 1 µg of cytokine.