Not available outside of the UK & Ireland.
Amino Acid Sequence
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]
Application
[Arg8]-Vasopressin acetate salt has been:used as a vasopressin receptor agonist to test vasopressin receptorsused to evoke peripheral V1a receptor-mediated vasoconstrictionas a supplement in Ham′s F12/Dulbecco′s modified Eagle′s medium for proximal tubule and glomerular explant cell culture
Biochem/physiol Actions
Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg8-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).
General description
Arginine vasopressin is a nonapeptide. It is produced by anterior hypothalamus nerve cells.
Other Notes
Lyophilized from 0.5% acetic acid
Preparation Note
[Arg8]-Vasopressin acetate salt dissolves water at 20 mg/ml to yield a clear colorless to faint yellow solution.
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