Not available outside of the UK & Ireland.

Application

Ubiquitin-Carrier Protein H10 (UbcH10) human may be used to study the role of ubiquitin-proteasome system in pathogenesis of human diseases.

Biochem/physiol Actions

Ubiquitin-Carrier Protein H10 human also referred to as UbcH10 is a recombinant protein that catalyzes the destruction of cyclin A as well as cyclin B along with the anaphase promoting complex and hence plays a pivotal role in controlling the cell exit from mitosis.

In conjunction with the anaphase-promoting complex, the protein catalyzes the destruction of both cyclin A and cyclin B.

General description

Manufactured for Sigma by Boston Biochem., Inc.

Physical form

Solution in 50 mM HEPES, pH 8.0, 125 mM NaCl, and 1 mM DTT in 10% glycerol.