Not available outside of the UK & Ireland.

Biochem/physiol Actions

UbcH9 mediates the conjugation of SUMO-1, SUMO-2, and SUMO-3 to a diverse variety of proteins without the help of an E3 ligase. This E2 conjugating enzyme interacts directly with protein substrates that are modified by SUMOylation, and may help in substrate recognition. UbcH9 is specific for the conjugation of proteins modified by SUMOylation.

General description

Manufactured for Sigma by Boston Biochem., Inc.

Physical form

Solution in 50 mM HEPES, pH 7.5, 100 mM NaCl, 10 % glycerol, 1mM TCEP.