Umbelliferyl Arachidonate, ethanol solution

Code: u0383-10mg D2-231

Not available outside of the UK & Ireland.

Application

Umbelliferyl Arachidonate also known as 7-Hydroxycoumarinyl Arachidonate was used as a fluorogenic substrate for developing a fluorescence-based assay to evaluate...


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$173.59 10MG
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Not available outside of the UK & Ireland.

Application

Umbelliferyl Arachidonate also known as 7-Hydroxycoumarinyl Arachidonate was used as a fluorogenic substrate for developing a fluorescence-based assay to evaluate the inhibitors against human recombinant monoacylglycerol lipase.

Biochem/physiol Actions

Monoacylglycerol lipase (MAGL) protein facilitates the hydrolysis of Umbelliferyl Arachidonate and generates arachidonic acid and the highly fluorescent 7-hydroxyl coumarin (7-HC). Hence, it acts as a marker in a fluorescence-based assay.

Preparation Note

Umbelliferyl Arachidonate can be dissolved in DMSO at 25 mg/ml and in DMF at 50 mg/ml. The product is sparingly soluble in aqueous buffers.

assay≥98% (HPLC)
biological sourcesynthetic (organic)
formethanol solution
InChI keySFTGFGOBCQCZDY-DOFZRALJSA-N
InChI1S/C29H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(30)32-26-22-20-25-21-23-29(31)33-27(25)24-26/h6-7,9-10,12-13,15-16,20-24H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15-
Quality Level200
shipped inwet ice
SMILES stringCCCCCC=C/CC=C/CC=C/CC=C/CCCC(=O)Oc1ccc2C=CC(=O)Oc2c1
solubilityDMF: soluble 50 mg/mL, DMSO: soluble 25 mg/mL, aqueous buffer: slightly soluble
storage temp.−20°C
technique(s)immunofluorescence: suitable
Hazard Class3
Un Number1170
Pack GroupII
This product has met the following criteria: