CDK2/CyclinA1, active, GST tagged human, PRECISIO Kinase, recombinant, expressed in baculovirus infected Sf9 cells, >=70% (SDS-PAGE), buffered aqueous glycerol solution

Code: srp5010-10ug D2-231

Not available outside of the UK & Ireland.

General description

CDK2 is a member of the Cyclin-Dependent Kinase family that is ubiquitously expressed. CDK2 is a catalytic subunit of the cyclin-dependent protein kinase ...


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£430.00 10UG

Not available outside of the UK & Ireland.

General description

CDK2 is a member of the Cyclin-Dependent Kinase family that is ubiquitously expressed. CDK2 is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. CDK2 associates with and is regulated by the regulatory subunits of the complex including Cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). CDK2 phosphorylates multiple cellular substrates including SMAD3 and FOXO1. Phosphorylation of FOXO1 leads to its inhibition.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
Gene Informationhuman ... CCNA1(8900), CDK2(1017)
mol wt~58 kDa (CDK1), ~81 kDa (CyclinA1)
NCBI accession no.NM_001798, BC036346
product linePRECISIO® Kinase
recombinantexpressed in baculovirus infected Sf9 cells
shipped indry ice
specific activity70-95 nmol/min·mg
storage temp.−70°C
This product has met the following criteria: