Reveromycin A, >=98% (HPLC), solid

Code: r0654-100ug D2-231

Not available outside of the UK & Ireland.

Analysis Note

Avoid acidic conditions.

Biochem/physiol Actions

It is an epidermal growth factor (EGF) and eukaryotic cell growth inhibitor.


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£296.00 100UG
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Not available outside of the UK & Ireland.

Analysis Note

Avoid acidic conditions.

Biochem/physiol Actions

It is an epidermal growth factor (EGF) and eukaryotic cell growth inhibitor.

Reveromycin A is a polyketide antibiotic from Streptomyces sp. Epidermal growth factor (EGF) inhibitor; apoptosis inducer; G1 phase cell cycle inhibitor having antiproliferative behavior against human cell lines KB and K562 as well as antifungal activity.

antibiotic activity spectrumfungi
biological sourceStreptomyces sp.
colortan
formsolid
InChI keyZESGNAJSBDILTB-OXVOKJAASA-N
InChI1S/C36H52O11/c1-6-7-19-35(47-34(44)17-16-32(40)41)21-22-36(46-30(35)14-10-25(3)23-33(42)43)20-18-27(5)29(45-36)13-9-24(2)8-12-28(37)26(4)11-15-31(38)39/h8-12,14-15,23,26-30,37H,6-7,13,16-22H2,1-5H3,(H,38,39)(H,40,41)(H,42,43)/b12-8+,14-10+,15-11+,24-9+,25-23+/t26-,27-,28-,29+,30-,35+,36-/m0/s1
mode of actionprotein synthesis | interferes
mol wt660.79 g/mol
packagingpkg of 100 µg
Quality Level200
shipped inwet ice
SMILES string[H][C@]1(CC=C(C)C=C[C@H](O)[C@@H](C)C=CC(O)=O)O[C@]2(CC[C@@H]1C)CC[C@@](CCCC)(OC(=O)CCC(O)=O)[C@@]([H])(O2)C=CC(C)=CC(O)=O
solubilitymethanol: soluble, DMF: soluble, soluble, ethanol: soluble, DMSO: soluble, ethyl acetate: soluble
storage temp.−20°C
Cas Number134615-37-5
This product has met the following criteria: