Human growth differentiation factor 15 (GDF-15) protein is a member of the TGFβ family and subject of intense interest as a marker of cellular stress and for its role in metabolism, cancer and pregnancy. Human GDF-15 also is functional in mouse studies.

Qkine GDF-15 is a 25 kDa disulphide-linked dimer composed of the mature domain of human GDF-15 protein. Our recombinant GDF-15 protein is exceptionally high purity, animal origin-free and extensively validated to ensure no trace contamination of related TGF-β family proteins from the mammalian culture systems.

• High purity human GDF-15 protein (Uniprot: Q99988)
• >98%, by SDS-PAGE quantitative densitometry
• 25 kDa (dimer). Mature active protein is a disulphide-linked dimer
• Expressed in E. coli
• Animal origin-free (AOF)
• Carrier protein-free
• Manufactured in our Cambridge, UK laboratories
• Lyophilised from acetonitrile, TFA
• Resuspend in 10mM HCl at >100µg/mL (provided with protein and free of charge), prepare single use aliquots, add carrier protein if desired and store frozen at -20°C or -80°C