pro1102

OVERVIEW
RANGE
SUSTAINABILITY

Transforming growth factor-beta 1 (TGF-β1) is a pleiotropic cytokine that regulates various cellular processes, including cell proliferation, growth, differentiation, motility, and apoptosis. It is an essential growth factor in many embryonic and induced pluripotent stem cell maintenance media, including the commonly used E8, StemPro, and mTeSR media. TGF-β1 also promotes the differentiation of various cell types such as fibroblasts, epithelial cells, and immune cells.

Human/bovine/porcine recombinant TGF-β1 PLUS™ protein is the first entirely animal origin-free recombinant human TGF-β1 protein for highly reproducible results and compatible with chemically-defined stem cell media.

TGF-β1 PLUS™ is a high purity 24 kDa dimer comprising optimised mature domain of TGF-β1 protein.

High purity optimised human/bovine/porcine TGF-β1 protein (Uniprot: P01137)
>98%, by SDS-PAGE quantitative densitometry
24 kDa (dimer)
Expressed in E. coli
Animal origin-free (AOF) and carrier protein-free.
Manufactured in our Cambridge, UK laboratories
Lyophilised from acetonitrile, TFA
Resuspend in 10mM HCl at >100µg/mL (provided with protein and free of charge), prepare single use aliquots, add carrier protein if desired and store frozen at -20°C or -80°C

This product has met the following criteria to qualify for the following awards:

	Sustainable Raw Material	Designed to reduce the use of raw materials
	Sustainable Product Manufacturing	Measures were in place during the manufacture of this product to reduce energy consumption Measures were in place during the manufacture of this product to generate less waste Measures were in place during the manufacture of this product to reduce water usage Aligns with the principles of green chemistry
	Sustainable Distribution & Packaging	Manufactured in the UK or Ireland Country of origin has an Environmental Performance Index (EPI) greater than 60 Plastic free packaging Product reduces need for packaging
	Sustainable Use	Product contributes to a reduced energy consumption Product contributes to a reduced water consumption Product reduces or replaces the need for consumables Built to last – minimum 5-year warranty, and spare part/servicing available
	Sustainable Disposal	A feature of this product enhances its biodegradability