pro1014

OVERVIEW
RANGE
SUSTAINABILITY

Activin A is a TGF–β family growth factor regulating embryonic development, cell proliferation, differentiation, and immune responses. Activin A is frequently used to maintain pluripotency in induced pluripotent and embryonic stem cell cultures. It is also used in many stem cell differentiation protocols, including endoderm lineage differentiation and further maturation into hepatocyte and pancreatic cells.

Recombinant human/mouse/rat/bovine/porcine activin A protein is a high-purity mature bioactive dimer of 26 kDa. It is animal origin-free, carrier protein-free, and tag-free to ensure its purity with exceptional lot-to-lot consistency. This protein has been rigorously benchmarked against other commercial sources and extensively validated for highly reproducible stem cell culture.

High purity mature bioactive dimer. Animal origin-free (AOF) and carrier-protein free (CF). Rigorously benchmarked against other commercial sources.

Bioactive mature domain of recombinant human activin A protein, residues 311-426, (Uniprot: P08476)
>98%, by SDS-PAGE quantitative densitometry
26 kDa (dimer)
Expressed in E. coli
Animal origin-free (AOF) and carrier protein-free.
Manufactured in our Cambridge, UK laboratories
Lyophilised from acetonitrile, TFA
Resuspend in 10mM HCl at >100µg/mL (provided with protein and free of charge), prepare single use aliquots, add carrier protein if desired and store frozen at -20°C or -80°C

This product has met the following criteria to qualify for the following awards:

	Sustainable Raw Material	Designed to reduce the use of raw materials
	Sustainable Product Manufacturing	Measures were in place during the manufacture of this product to reduce energy consumption Measures were in place during the manufacture of this product to generate less waste Measures were in place during the manufacture of this product to reduce water usage Aligns with the principles of green chemistry
	Sustainable Distribution & Packaging	Manufactured in the UK or Ireland Country of origin has an Environmental Performance Index (EPI) greater than 60 Plastic free packaging Product reduces need for packaging
	Sustainable Use	Product contributes to a reduced energy consumption Product contributes to a reduced water consumption Product reduces or replaces the need for consumables Built to last – minimum 5-year warranty, and spare part/servicing available
	Sustainable Disposal	A feature of this product enhances its biodegradability