Not available outside of the UK & Ireland.

Application

20S proteasome fraction from rabbit has been used as a positive control to determine proteasome activity.

Biochem/physiol Actions

Hydrolyzes various peptide substrates and proteins with broad specificity in a non-ATP dependent process.

Catalytic core of the 26S proteasome that degrades polyubiquitinated proteins.

General description

Manufactured for Sigma by Boston Biochem., Inc.

Physical form

Solution in 50 mM HEPES, pH 7.6, 150 mM sodium chloride, and 1 mM DTT, pH 7.6.