Not available outside of the UK & Ireland.

Application

O-Phospho-L-serine has been used:for the expression, purification and phosphorylation of proteinto study its chemical shift to spectroscopically determine its pKa values using Raman spectroscopy

Biochem/physiol Actions

O-Phospho-L-serine (L-SOP) is a molecule which resembles phosphatidylserine head group and it mediates partial inhibition of microglial phagocytosis of apoptotic cells. In zebrafish, L-SOP inhibits Müller glia proliferation and blocks cone cell regeneration in the light-damaged retina. In vivo, L-SOP acts as a substrate for CysM, a cysteine synthase from Mycobacterium tuberculosis.

Group III metabotropic glutamate receptor agonist (mGluR₄, mGluR₇, and mGluR₈).

Packaging

10 mg in autosample vial