Not available outside of the UK & Ireland.

Analysis Note

The biological activity is measured by its ability to induce chemotaxis in IL-2 cultured human lymphocytes.

Biochem/physiol Actions

I-TAC (Interferon-inducible T-cell α chemoattractant) is a chemokine which participates in recruitment of inflammatory cell. It binds to receptor CXCR3 (C-X-C motif chemokine receptor 3). I-TAC is associated with the severity of dengue.

Physical form

Lyophilized in 30% acetonitrile and 0.1% trifluoroacetic acid containing 1.25 mg of bovine serum albumin.