Not available outside of the UK & Ireland.

Analysis Note

The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.

Biochem/physiol Actions

Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.

General description

Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.

Physical form

Lyophilized, 0.2 µm sterile filtered, with with 0.5x PBS.