Not available outside of the UK & Ireland.

Amino Acid Sequence

Val-Pro-Met-Leu-Lys

Biochem/physiol Actions

Bax-mediated apoptosis inhibitor; membrane permeable pentapeptide based on the Ku70-Bax inhibiting domain.

BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet and anti-cancer drug.

Other Notes

Lyophilized from 0.1% TFA in H2O