L-2-Aminoadipic acid, >=98% (TLC)

Code: a7275-100mg D2-231

Not available outside of the UK & Ireland.

Application

L-2-Aminoadipic acid has been used as a gliotoxin specific for astrocytes in rat. It has also been as an internal standard in the amino acid analysis from ferment...


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£63.50 100MG
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Not available outside of the UK & Ireland.

Application

L-2-Aminoadipic acid has been used as a gliotoxin specific for astrocytes in rat. It has also been as an internal standard in the amino acid analysis from fermented food sample.

Biochem/physiol Actions

L-2-Aminoadipic acid inhibits glutamine synthetase and γ-glutamylcysteine synthetase. It modulates glucose metabolism and is present in higher levels in diabetic patients. L-2-Aminoadipic acid plays a key role in suppressing autophagy in C2C12 myotubes.

General description

L-2-Aminoadipic acid/α-aminoadipate is a gliotoxin and is a structural analog of glutamine. It is generated by the catabolism of lysine saccharopine (SAC)/pipecolic acid (PIP) pathways.

Packaging

1, 5 g in poly bottle

100, 250 mg in poly bottle

assay≥98% (TLC)
formpowder
Gene Informationhuman ... GLUL(2752), LGSN(51557)rat ... Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418), Grm6(24419)
InChI keyOYIFNHCXNCRBQI-BYPYZUCNSA-N
InChI1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m0/s1
mp203-205 °C (dec.) (lit.)
Quality Level200
SMILES stringN[C@@H](CCCC(O)=O)C(O)=O
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Description
Unit Size
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A7275-1G
L-2-Aminoadipic acid, >=98% (TLC)

Unit:1G
List Price: £381.00
Source:List Price
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A7275-250MG
L-2-Aminoadipic acid, >=98% (TLC)

Unit:250MG
List Price: £79.30
Source:List Price
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A7275-5G
L-2-Aminoadipic acid, >=98% (TLC)

Unit:5G
List Price: £889.00
Source:List Price
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Cas Number1118-90-7
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