N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, >=97% (HPLC), powder

Code: a6220-5mg D2-231

Not available outside of the UK & Ireland.

Amino Acid Sequence

NAc-Ile-Glu-Pro-Asp-AMC

Substrates

Fluorogenic substrate for caspase 8 and granzyme B.


 

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$596.92 5MG
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assay≥97% (HPLC)
formpowder
Gene Informationhuman ... CARD8(22900), CASP8(841), CASP8AP2(9994), CFLAR(8837), GZMB(3002)mouse ... CFLAR(117279), GZMB(171528)rat ... CASP8(12370), CFLAR(12633), GZMB(14939), RGD1561819(502004), RGD1562700(502007)
InChI keyXDMHHBKPMUGLEA-MNTOYCOOSA-N
InChI1S/C32H41N5O11/c1-5-16(2)28(33-18(4)38)31(46)35-21(10-11-25(39)40)32(47)37-12-6-7-23(37)30(45)36-22(15-26(41)42)29(44)34-19-8-9-20-17(3)13-27(43)48-24(20)14-19/h8-9,13-14,16,21-23,28H,5-7,10-12,15H2,1-4H3,(H,33,38)(H,34,44)(H,35,46)(H,36,45)(H,39,40)(H,41,42)/t16-,21-,22-,23-,28-/m0/s1
Quality Level200
shipped indry ice
SMILES stringCC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2
solubilityDMSO/DMF: 1 mg/mL
storage temp.−20°C
This product has met the following criteria: