Not available outside of the UK & Ireland.
Amino Acid Sequence
NAc-Asp-Glu-Val-Asp-al
Application
N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.
Biochem/physiol Actions
N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.
Reversible inhibitor of IL-1β converting enzyme (ICE); inhibits poly(ADP-ribose) polymerase cleavage by apopain (caspase 3).
General description
N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.
This product has met the following criteria: