Not available outside of the UK & Ireland.

Application

MSDH is suitable is suitable to induce lysosomal membrane destabilization toinvestigate the mechanistic basis for Bax/Bak-mediated autophagic cell death.

Biochem/physiol Actions

O-methyl-serine-dodecylamidehydrochloride(MSDH) stimulatescell death. After apoptosis, it may activate procaspase 3-like proteases and cause partial lysosomal rupture.

General description

O-methyl-serine-dodecylamide hydrochloride (MSDH) is a synthetic lysosomotropicdetergent.

Packaging

5 mL Amber Glass Screw Cap Vial (850546P-25mg)