Not available outside of the UK & Ireland.
Application
Reagent for the covalent modification of cysteine residues in proteins.
N-Ethylmaleimide has been used to measure low molecular weight thiols bound to plasma proteins.
Biochem/physiol Actions
Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.
Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.
This product has met the following criteria: