N-Ethylmaleimide, purum p.a., >=99.0% (HPLC)

Code: 04260-5g-f D2-231

Not available outside of the UK & Ireland.

Application

Reagent for the covalent modification of cysteine residues in proteins.

N-Ethylmaleimide has been used to measure low molecular weight thiols bound...

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Not available outside of the UK & Ireland.

Application

Reagent for the covalent modification of cysteine residues in proteins.

N-Ethylmaleimide has been used to measure low molecular weight thiols bound to plasma proteins.

Biochem/physiol Actions

Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.

Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.

anion traces	sulfate (SO₄^2-): ≤100 mg/kg, chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤300 mg/kg, chloride (Cl^-): ≤200 mg/kg
assay	≥99.0% (HPLC), 98-103%, ≥98%
bp	210 °C (lit.)
cation traces	Fe: ≤50 mg/kg, Cd: ≤50 mg/kg, K: ≤100 mg/kg, Cu: ≤50 mg/kg, Na: ≤100 mg/kg, Pb: ≤50 mg/kg, Co: ≤50 mg/kg, Zn: ≤50 mg/kg, Ca: ≤50 mg/kg, Ni: ≤50 mg/kg, Fe: ≤50 mg/kg, Ba:, in accordance, As: ≤1 mg/kg
density	2.123 g/mL at 25 °C (lit.)
Gene Information	human ... SLC6A3(6531), SLC6A4(6532)
grade	purum p.a., puriss. special
ign. residue	≤0.05%
impurities	≤0.002% heavy metals (as Pb), Mg,-Mg-dihydrogen phosphate, in accordance
InChI key	HDFGOPSGAURCEO-UHFFFAOYSA-N, OKIWLDVQGKRUNR-UHFFFAOYSA-L
InChI	1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3, 1S/Mg.H3O4P.3H2O/c;1-5(2,3)4;;;/h;(H3,1,2,3,4);3*1H2/q+2;;;;/p-2
mp	43-46 °C, 43-46 °C (lit.)
Quality Level	200, 200
quality	meets analytical specification of DAB
SMILES string	CCN1C(=O)C=CC1=O, [Mg++].[H]O[H].[H]O[H].[H]O[H].OP([O-])([O-])=O
storage temp.	2-8°C

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04260-25G-F

Unit:25G

List Price: £254.00

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