Not available outside of the UK & Ireland.

Application

For research use only. Not for use in diagnostic procedures.Please refer to the attached Protocolfor details.

Biochem/physiol Actions

BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) acts as an inhibitor of TGF-β (transforming growth factor β receptor) signalling which causes epithelial-mesenchymal transition. Upregulation of BAMBI gene is observed in chronic obstructive pulmonary disease and a number of cancer including thyroid, liver, colorectal cancer and ovarian cancer. BAMBI might regulate the events of inflammation and remodeling processes.

General description

BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) gene codes for a transmembrane glycoprotein which is a pseudo receptor belonging to the family of TGF-β (transforming growth factor β receptor) type I receptors. BAMBI is predominantly expressed in placenta, spleen and kidney medulla and also found liver, prostate, gut and kidney cortex.

This ELISA antibody pair detects Human BAMBI. Other species not yet determined.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.