Not available outside of the UK & Ireland.

Application

For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

FER tyrosine kinase induces signal transduction at the plasma membrane. It is implicated in the regulation of cell-cell adhesion. FER tyrosine kinase interacts with phosphatidic acid (PA) to enhance phosphorylation of cortactin, a protein that promotes actin.

General description

FER (fps/fes related) tyrosine kinase is encoded by the gene mapped to human chromosome 5q21.3. Tyrosine kinase is a cytoplasmic protein characterized with a single SH2 domain and an extensive amino terminus. The encoded protein is ubiquitously expressed.

The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-FER.