Not available outside of the UK & Ireland.

Application

For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Oxidized low-density lipoprotein receptor 1 (OLR1), also referred as Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), acts as a scavenger receptor for oxidized low-density lipoprotein (ox-LDL). It is essential for formation and progression of atherosclerotic plaques. Therefore, mutation in the gene increases the risk of susceptibility to atherosclerotic-related diseases. In addition, genetic variation in the gene leads to myocardial infarction. Serum concentration of OLR1 serves as an efficient biomarker of intracerebral hemorrhage (ICH).

General description

The antibody pair provided in this kit recognizes mouse Oxidized Low-density Lipoprotein Receptor 1.