Not available outside of the UK & Ireland.

Application

For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Hemoglobin (Hb) serves as the primary means of oxygen transport in vertebrates. Hb exhibits antioxidant and antimicrobial activity. Alterations in blood hemoglobin levels occur in many diseases such as anemia and polycythemia. In addition, abnormalities in Hb concentration might be implicated in pathologies associated with various respiratory diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive lung disease (COPD).

General description

The antibody pair provided in this kit recognizes Human Hemoglobin. Hemoglobin (Hb) is an iron-containing metalloprotein, which is highly expressed in red blood cells. In addition, it is also expressed in nonerythroid cells such as epithelial cells of different origin. Hb is a tetramer composed of two α-globin chains and two β-globin chains. α-globin and β-globin chains is encoded by a gene mapped to human chromosome 16 and 11, respectively.

Other Notes

A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.