Not available outside of the UK & Ireland.
Application
For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Insulin-like growth factor-binding protein 3 (IGFBP3) is implicated in cell survival. In addition, it also facilitates cell death and tumorigenesis. Epigenetic changes in IGFBP3 affect non-small-cell lung cancer, hepatocellular carcinoma, ovarian cancer, skin cancer, urological cancers, breast cancer and gastric cancer. IGFBP3 is a primary growth inhibitor and can reverse the mitogenic functions of IGF-1 (insulin like growth factor 1) by inducing apoptosis.
General description
The Human IGFBP-3 ELISA (Enzyme-Linked mmunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IGFBP-3 in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human IGFBP3
Other Notes
A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.
This product has met the following criteria: