Not available outside of the UK & Ireland.

Application

N-Butyldeoxynojirimycin has been used:in the inhibition of glycolipid synthesis in neuroblastoma cellsin the inhibition the ceramide-specific glycosyltransferase in hepatocytesin the inhibition of β-glucosidase (GBA2) using fluorescence- activity assay in human embryonic kidney (HEK293) cells.

Biochem/physiol Actions

N-Butyldeoxynojirimycin is an inhibitor of glucosyltransferase and α-glucosidases. N-Butyldeoxynojirimycin, also known as misglustat, reduces glycolipid levels by substrate reduction therapy (SRT) and is effectively used for the treatment of glycosphingolipid lysosomal storage disorder, Gaucher disease.

α-glucosidase Inhibitor

General description

N-Butyldeoxynojirimycin is an alkylated product of imino sugar deoxynojirimycin.

Packaging

1, 5 mg in glass bottle