Not available outside of the UK & Ireland.

Application

For research use only. Not for use in diagnostic procedures.Human RAGE / AGER ELISA kit has been used for the quantitative measurement of RAGE in cerebrospinal fluid.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Advanced glycosylation end-product specific receptor (AGER) or RAGE is part of the immunoglobulin superfamily of cell surface molecules. The soluble form of the protein has a function in the Wnt pathway. RAGE has a role in the development of inflammatory and cellular damage, as well as cellular toxicity. It has been associated with diabetic atherosclerosis. AGER/RAGE also modulates cell proliferation, differentiation and apoptosis.(6}

General description

The Human RAGE ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human RAGE in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human RAGE

Other Notes

A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.