Not available outside of the UK & Ireland.

Application

The SILu^™MAb K1 Pharmacokinetic (PK) kit enables a robust, high-throughput assay for quantification of human IgG1 antibody in animal sera by LC-MS/MS.

General description

All critical reagents necessary to perform the assay are provided in the kit. The plate-based format avoids the high cost and potential LC column blockage associated with bead-based enrichment formats. Sample preparation with the SILu^™MAb PK kit can be performed in under 5 hours and consists of coating wells with high-specificity capture antibody, followed by immunoaffinity enrichment and rapid, in-plate trypsin digestion. The resulting digest is ready for injection, with no SPE or other cleanup required.

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Storage and Stability

Store the kit at 2-8°C. The kit is stable for two years refrigerated.