POLY(D;L-LACTIDE-CO-GLYCOLIDE)-BLOCK-PO+

Code: 790257-1g D2-231

Not available outside of the UK & Ireland.

Application

This poly(ether ester urethane) based on PLGA-PEG-PLGA triblock copolymers linked with a diisocyanate is a biodegradable; resorbable gel former for use in drug de...


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$213.77 1G
$256.52 inc. VAT
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Not available outside of the UK & Ireland.

Application

This poly(ether ester urethane) based on PLGA-PEG-PLGA triblock copolymers linked with a diisocyanate is a biodegradable; resorbable gel former for use in drug delivery systems. This polymer doesn’;t rely on temperature or pH to induce gelation and therefore form more consistent and faster-setting drug delivery depots. Through combination of various gel formers and/or diluents; drug release profiles may be modulated to exhibit fast burst release through extended (up to 1 month) zero-order release profile.

Packaging

1, 5 g in glass bottle

degradation timeframe﹤4 months
feed ratiolactide:glycolide 1:0.8, PEG:DL-lactide:glycolide 19:65:16, (Prepolymer (PLGA-PEG-PLGA): Diisocyanate :: 1:0.8)
formpaste
mol wtPEG average Mn 400, average Mn 6,000-12,000
PDI﹤2.0
Quality Level100
SMILES stringCC(N[R]NC(OC(C)C(OCC(OCCOC(C(C)OC(COC)=O)=O)=O)=O)=O)=O.CC(N[R]NC(OCCCOC)=O)=O
storage temp.2-8°C
transition tempTg ﹤0 °C
viscosity8.79 Pa.s(100 °C) (at Angular Frequency (1/s) 5.46 Anton-Parr Rhometer), 466 Pa.s(50 °C) (at Angular Frequency (1/s) 1.33, Anton-Parr Rhometer)
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Description
Unit Size
List Price
Qty
790257-5G
POLY(D;L-LACTIDE-CO-GLYCOLIDE)-BLOCK-PO+

Unit:5G
List Price: $728.13
Source:List Price
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