Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide), PEG Mn 2,000, PLGA Mn 4,000

Code: 764825-1g D2-231

Not available outside of the UK & Ireland.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

forming "stealth" pegylated microp...


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Your Price
$369.69 1G
$443.63 inc. VAT

Not available outside of the UK & Ireland.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

forming "stealth" pegylated microparticles

Features and Benefits

Good biocompatibility, low immunogenicity and good degradability.Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

General description

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.

Packaging

1 g in glass bottle

degradation timeframe1-4 weeks
feed ratiolactide:glycolide 65:35
formpellets
mol wtPLGA Mn 4,500, average Mn 6,500 (total), PEG Mn 2,000
PDI≤2.0
Quality Level100
storage temp.2-8°C
transition tempTm 241-246 °C
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