Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide), average Mn (1100-1000-1100)

Code: 764817-1g D2-231

Not available outside of the UK & Ireland.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Features and Benefits

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Your Price
$652.59 1G
$783.11 inc. VAT

Not available outside of the UK & Ireland.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Features and Benefits

Biocompatible, degradable, thermosensitive, high stability, small size (﹤200 nm) and properties can be easily modified.

General description

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.

Packaging

1 g in glass bottle

degradation timeframe2-3 weeks
descriptiontypical PEG PDI﹤1.1; overall PDI≤2.0 (THF, PS)
feed ratiolactide:glycolide 75:25
formsemisolid
mol wtaverage Mn (1100-1000-1100), PLGA average Mn 2,200, PEG average Mn 1,000
PDI﹤2.0
Quality Level100
storage temp.2-8°C
transition tempTm 230-235 °C
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