Poly(ethylene glycol) methyl ether-block-poly(D,L lactide),

Code: 764779-1g D2-231

Not available outside of the UK & Ireland.

Application

water-solubilization of drugs

Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs.

Features and Benefits...


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Your Price
£284.95 1G

Not available outside of the UK & Ireland.

Application

water-solubilization of drugs

Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs.

Features and Benefits

Good biocompatibility, low immunogenicity and good degradability.Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

General description

Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as carriers for hydrophobic drugs like paclitaxel. PEG is the hydrophilic part and PDLLA is the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.

Packaging

1 g in glass bottle

degradation timeframe2-4 weeks
descriptionn=45, m=28 (typical), typical PEG PDI﹤1.1; overall PDI﹤1.4 (THF, PEO)
formpellets
mol wtPDLLA average Mn 2,000, PEG average Mn 2,000, average Mn 4,000 (total)
PDI≤1.4
Quality Level100
storage temp.2-8°C
transition tempTg 11 °C (PEG block), Tg 88 °C (PDLLA block), Tm 244-248 °C
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