Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)-block-decane, PEG average Mn 2,000, PLA average Mn 2,000

Code: 764736-1g D2-231

Not available outside of the UK & Ireland.

Application

Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs.

Features and Benefits

Good biocompatibilit...


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Your Price
£561.26 1G
£673.51 inc. VAT

Not available outside of the UK & Ireland.

Application

Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs.

Features and Benefits

Good biocompatibility, low immunogenicity and good degradability.Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

General description

Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as a carrier for hydrophobic drugs like Paclitaxel. The hydrophilic PEG and hydrophobic PDLLA form the micelle core wherein the hydrophobic drug is loaded. The incorporation of the 10-alkyl end cap (decane) increases the hydrophobicity of the micelle core and increases its solubilizing capability for hydrophobic drugs.†

Packaging

1 g in glass bottle

degradation timeframe2-5 weeks
formpellets
mol wtPDLLA average Mn 2,000, PEG average Mn 2,000, average Mn 4,000 (total)
PDI﹤1.1 (typical PEG), ﹤1.3 (overall), ﹤1.2
Quality Level100
storage temp.2-8°C
transition tempTm 29-33 °C
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