Not available outside of the UK & Ireland.

Application

Ribonucleoside vanadyl complexes has been used:as a component of lysis buffer for cell lines prior to Poly(U) pull down assayto inhibit nucleases prior to immunoprecipitation (IP) of m6A-containing RNA fragmentas a component of hybridization buffer for human retinal slices

Ribonucleoside vanadyl complexes are used as ribonuclease inhibitors during cell lysis and mRNA purification, to protect mRNA during cDNA production, and to protect RNA during digestion of DNA by DNaseI.

Biochem/physiol Actions

Ribonucleoside vanadyl complexes (RVC) elicits antimicrobial functionality by inhibiting ribosomal subunit formation and suppressing the growth of Staphylococcus aureus and Escherichia coli. It is also used as a preservative solution for tissues.

General description

Ribonucleoside vanadyl complexes are stable complexes formed between ribonucleotides. They are low molecular weight inhibitors of cellular ribonucleases (RNases) that are used for the isolation of RNA from cells.