ROCHE Mitomycin C

Code: 10107409001 D2-231

Not available outside of the UK & Ireland.

Application

Mitomycin C is used as an inhibitor for studies of cell-free protein biosynthesis. It also inhibits DNA synthesis. It has been used as a genotoxic agent for tumor...


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Not available outside of the UK & Ireland.

Application

Mitomycin C is used as an inhibitor for studies of cell-free protein biosynthesis. It also inhibits DNA synthesis. It has been used as a genotoxic agent for tumor cells.

Mitomycin C has been used: to cease mitosisin phosphate buffer saline (PBS)for inactivation and plating mouse embryonic fibroblasts (MEFs)as mutagen in mutagenicity assay

Biochem/physiol Actions

Mitomycin C (MMC) acts as a prototype for drugs with bioreductive alkylation. It is mainly found to be active under anaerobic conditions.MMC exhibits a vast clinical antitumor spectrum effectively in gastric, pancreatic and breast cancer.

General description

Mitomycin C is an antitumor antibiotic.

Other Notes

For life science research only. Not for use in diagnostic procedures.

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria
assay98%
formcrystalline powder
InChI keyNWIBSHFKIJFRCO-WUDYKRTCSA-N
InChI1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
manufacturer/tradenameRoche
mode of actionDNA synthesis | interferes
mol wt334.3
packagingpkg of 2 mg
Quality Level100
storage temp.2-8°C
Hazard Class6.1
Un Number2811
Pack GroupII
This product has met the following criteria: