Not available outside of the UK & Ireland.

Application

Tetrazole solution is useful for DNA synthesis. It may be employed as a catalyst for the in situ synthesis of deoxyribonucleoside phosphoramidites. It may be used in the preparation of following anionic nucleotide-lipids:thymidine 3′-(1,2-dilauroyl-sn-glycero-3-phosphate) , diC₁₂-3′-dTthymidine 3′-(1,2-dimyristoyl-sn-glycero-3-phosphate) diC₁₄- 3′-dTthymidine-3′-(1,2-dipalmitoyl-sn-glycero-3-phosphate) diC₁₆- 3′-dT

Caution

Saturated solution at room temperature; storage below room temperature causes precipitation.

General description

The product is ~0.45M solution of tetrazole in acetonitrile. Tetrazole ring plays significant role in various synthetic and industrial processes.

Other Notes

Catalyst used in the phosphite triester method of oligonucleotide synthesis for the coupling of (dialkylamino)phosphines

Packaging

100, 500 mL in Sure/Seal™