Not available outside of the UK & Ireland.

Application

Thymidine 5′-triphosphate (dTTP) is one of the four natural deoxynucleotides, along with deoxyadenosine 5’-triphosphate (dATP), deoxyguanosine 5’-triphosphate (dGTP) and deoxycytosine 5’-triphosphate (dCTP) used for the biosynthesis of deoxyribonucleic acids by DNA polymerases and reverse transcriptases. Deoxy-TTP may also be used as a substrate to study the specificity and kinetics of thymidine-triphosphatase(s) (EC 3.6.1.39) and other dTTP hydrolyzing activities.

Thymidine 5′-triphosphate sodium salt has been used:in the quenching ability test for dual-aptamer and multiple-nucleotide detection based on a multiple-aptamer/GO-nS complexto study protein-metabolite interactions in the central metabolism of Escherichia coliin a polymerase chain reaction (PCR) product formation using AM-toxin primers

Biochem/physiol Actions

Thymidine triphosphate is a building block of DNA. It acts as an allosteric regulator of other nucleotides′ metabolism.

Packaging

10, 25, 50 mg in poly bottle

250 mg in glass bottle