Not available outside of the UK & Ireland.
Application
Adenosine, periodate oxidized has been used: as a methylarginine transferase inhibitor in the human embryonic kidney (HEK)-293 T cells as a methylase inhibitor in H4 neurogliomaas a broad inhibitor of S-adenosylmethionine (AdoMet)-dependent methyltransferases in mouse embryo fibroblast NIH3T3 cells
Biochem/physiol Actions
Adenosine, periodate oxidized (Adox) is a protein arginine methyltransferases (PRMTs) inhibitor. It also inhibits the enzyme S-adenosylhomocysteine hydrolase and induces apoptosis. Its inhibitory effect on histone methyltransferases prevents histone methylation. Adox also elicits intrinsic cytotoxic properties.
Packaging
25, 100 mg in poly bottle
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