Not available outside of the UK & Ireland.

Application

NanoFabTx^™ Microfluidic - micro device kit in combination with the NanoFabTx^™ - micro reagent kits (Cat. No. 912212) can be used to create drug-encapsulating polymeric microparticles 10-30 µm in size. Because of the adjustable flow rate, small reaction window, and adjustable concentrations, microfluidic-based synthesis is a powerful tool for fabricating size-controlled particles to encapsulate drugs, small molecules, mRNA, DNA, and proteins. The chip geometries and flow parameters enable facile, scalable synthesis of monodispersed particles with consistent size and drug loading to facilitate rapid formulation screening.

Features and Benefits

Simplifies polymer chemistry of microfluidic formulation development for enhancing drug bioavailability Accelerates optimization of drug encapsulation and loading efficiency in microparticles Provides step-by-step microfluidic-based protocols developed and tested by our formulation scientists Minimizes waste of expensive reagents

General description

NanoFabTx^™ Microfluidic - micro device kit is designed to work with the NanoFabTx^™ - micro reagent kits like (Cat. No. 912212) for the synthesis of 10-30 µm particles. The device kit includes a comprehensive protocol, pre-assembled microfluidic chip manifold, tubing, and required accessories and is compatible with either the Dolomite microfluidics system or a standard syringe pump (compatible microfluidics system or syringe pump required separately).

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC