FOLATE-POLY(ETHYLENE GLYCOL)-B-POLY(LAC+

Code: 909769-50mg D2-231

Not available outside of the UK & Ireland.

Application

Folate-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG ...


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£254.73 EACH

Not available outside of the UK & Ireland.

Application

Folate-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The folate functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

colorwhite to tan
feed ratiolactide:glycolide 50:50
formpowder or chunks
mol wtPLGA average Mn 10,000 (by NMR), PEG average Mn 2,000 (by NMR)
storage temp.−20°C
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