Not available outside of the UK & Ireland.
Application
DC-Cholesterol HCl is suitable: for the preparation of ultrasound cationic microbubbles to prepare liposomes for the preparation of L-glutathione (GSH), loaded proliposomes
DC-Cholesterol HCl may be used in the preparation of colloidal dispersions for transmission electron microscopy studies. It may also be used in liposome preparation for assessing hexokinase activity, poly (lactic-coglycolicacid) loading and in mRNA transfection studies.
Biochem/physiol Actions
DC-cholesterol is a cationic lipid, known to be the most efficient in gene transfection study.
DC-Cholesterol is an effective transfection agent and a liposome reagent. Liposome of DC-Cholesterol with dioleoylphosphatidylethanolamine (DOPE) are efficient for DNA transfection. It imparts positive surface charge to the microbubbles for ultra sound based transfection of clustered regularly interspaced short palindromic repeats (CRISPRs).
General description
DC-Cholesterol HCl is a cholesterol derivative and a cationic lipid with a head group and linker moiety.
DC-Cholesterol HCl is a sterol-based transfection reagent.
Packaging
20 mL Clear Glass Screw Cap Vial (700001P-500mg)
20 mL Clear Glass Screw Cap Vial (700001P-1g)
5 mL Amber Glass Screw Cap Vial (700001P-200mg)
5 mL Amber Glass Screw Cap Vial (700001P-25mg)
This product has met the following criteria: