Not available outside of the UK & Ireland.

Application

Cuprizone (Bis(cyclohexanone)oxaldihydrazone) was used for toxic demyelination in the central nervous system in order to investigate the pathobiology of remyelination in the corpus callosum, so as to study the human demyelinating diseases such as multiple sclerosis. It was also used a model to study components of neuroinflammation.

General description

Cuprizone (Bis(cyclohexanone)oxaldihydrazone) is a physically unstable compound and is a well-known neurotoxic agent.

Other Notes

In the presence of a copper salt, this ligand catalyzes Ullmann-type C-N bond forming reactions under mild, aqueous conditions.

For the spectrophotometric determination of Cu(II)